(Trans)-Pterostilbene CAS 537-42-8 Anti-cancer Anti-inflammatory Herbal extract Natural product Dietary supplement

Description

Pterostilbene is a fragrant-smelling hydrocarbon called "styrene", which is a derivative of resveratrol. It is found in blueberries and Pterocarpus marsupium (PM) heartwood. It has anti-inflammatory, anti-thrombotic, anti-cancer, anti-cancer, anti-hyperlipidemia and antibacterial effects. 

Chemical Formula:

Existance 

Pterostilbene is a natural molecule found in fruits, vegetables and nuts. Blueberries are often quoted as one of the richest sources of pterostilbene. It is also found in almonds,various Vaccinium berries (including blueberries), grape leaves and vines,and Pterocarpus marsupium heartwood.

Preparation

Pterostilbene was synthesized from 3,5-dimethoxybenzyl bromide and p-nitrobenzaldehyde by Witting-Hornor reaction, reduction, diazotization and hydrolysis, with a total yield of 53.9%.

Benefits

Pterostilbene is a naturally-derived stilbenoid structurally related to resveratrol, with potential antioxidant, antiinflammatory, pro-apoptotic, antineoplastic and cytoprotective activities. Pterostilbene is known to have many pharmacological benefits for the prevention and treatment of a wide variety of diseases, including ( cancer (McCormack and McFadden 2012), dyslipidaemia (Rimando et al. 2005), diabetes (Amarnath Satheesh and Pari 2006), cardiovascular degeneration (Amarnath Satheesh and Pari 2008) and pain (Hougee et al. 2005).

What are the risks of taking pterostilbene?

Pterostilbene is considered safe, and no adverse effects have been reported up to a dose of 250 mg per day. However, some people may experience increased LDL cholesterol when using it. Given this compound is commonly found in food, dietary levels of pterostilbene should be safe.

What is pterostilbene supplement?

Potent Antioxidant; Experiments suggest that Pterostilbene acts as a potent antioxidant by binding to PPAR receptors and supporting the production of the compound. Supports Brain Cell Health: Pterostilbene may help support cognitive function. Supports Healthy Aging; Pterostilbene may help support healthy aging.

Who should take pterostilbene?

It looks promising, but has significantly less research than its predecessor. Pterostilbene is most often used for Healthy Aging & Longevity and Cardiovascular Health. The Examine Database covers Coronary Artery Disease,High Blood Pressure, and 3 other conditions and goals.

How does pterostilbene affect the brain?

Pterostilbene Increased Antioxidant Effect and Inhibited Neuronal Apoptosis in Alzheimer's Disease Mice. To evaluate the protective effect of PTE on mitochondrial function, the level of apoptosis was determined.  

How does pterostilbene affect the brain?

Pterostilbene Increased Antioxidant Effect and Inhibited Neuronal Apoptosis in Alzheimer's Disease Mice. To evaluate the protective effect of PTE on mitochondrial function, the level of apoptosis was determined. 

What is the best source of pterostilbene?

blueberries

Pterostilbene (PTS), a compound most abundantly found in blueberries, is a natural analog of resveratrol. Several plant species, such as peanuts and grapes, produce PTS.  

How much pterostilbene should I take a day?

Pterostilbene is considered safe, and no adverse effects have been reported up to a dose of 250 mg per day. However, some people may experience increased LDL cholesterol when using it. Given this compound is commonly found in food, dietary levels of pterostilbene should be safe.

References:

1. https://www.lifespan.io

2. Chemical book www.chemicalbook.com

3.https://www.amazon.com

4.https://examine.com

5.https://www.frontiersin.org

6.https://www.frontiersin.org

7.https://www.ncbi.nlm.nih.gov